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Neuroprotective Effect of Cuscuta chinensis Lam Extract on the Neuronal Differentiated PC12 Cells Damage Induced by Reactive Oxygen Species
Li-Hua Wang, Peng-Cheng Bu, Yong-Ming Bao*
Department of Bioscience and Biotechnology, Dalian University of Technology, Dalian 116024, China
Abstract: The pharmacology and clinical application of traditional Chinese medicine has been extensively documented. In the present study, with the comparison of the expression of apoptosis proteins p53, Bax and Bcl-2, and the level of superoxidase, glutathione, malondialdehyde of neuronal differentiated PC12 cells in the absence and/or presence of Cuscuta chinensis Lam extract, we found that Cuscuta chinensis Lam extract, in a dose-dependent manner, prevents the neuronal differentiated PC12 cells damage from reactive oxygen species.