The Role of Ubiquitination in Antiviral Innate Immune Response

The post translational modification of proteins regulates almost all the life activities of cells. A large number of studies have reported the role of ubiquitination in the process of viral infection. When infected with the virus, host cells can initiate an antiviral innate immune response to restrict viral infection, and correspondingly, viruses can escape the cellular immune response, through ubiquitination pathways. This paper reviews the role and regulatory mechanism of protein ubiquitination from both host and virus perspectives, providing some new strategies for future antiviral treatments.

CSTR: 32200.14.cjcb.2023.05.0013