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Components of Chicken Ovalbumin Extract Less Than 3 kDa in Size Promote Cell Proliferation
Ruan Guangping, Wang Jinxiang, Liu Jufen, Shu Fan, Yang Jianyong, Pang Rongqing, Pan Xinghua*
Stem Cell Engineering Laboratory, Kunming General Hospital of PLA, Kunming 650032, China
Abstract: We found that chicken egg extract could promote cell survival and proliferation. In this study， we further separated the components of chicken egg extract to find the main ingredient promoting cell proliferation. The chicken ovalbumin extract was separated into more than 3 kDa and less than 3 kDa components by ultrafiltration， and then their effect on cell proliferation activity were determined. Less than 3 kDa ingredients in chicken ovalbumin extract can promote 293T cell proliferation. We can separate less than 3 kDa fraction in the chicken ovalbumin as an active ingredient to promote 293T cell proliferation.
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