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Kisspeptins/GPR54 System and Reproduction Regulation in Mammal
Zhang Wei1,2,3, Wang Shiyin1, Gan Shangquan2, Shi Guoqing2*
1College of Animal Science and Technology, Xinjiang Agricultural Professional Technological College, Changji 831100, China; 2Institute of Animal Husbandry and Veterinary, Xinjiang Academy of Agricultural and Reclamation Sciences, Shihezi 832000, China; 3College of Animal Science and Technology, Shihezi University, Shihezi 832003, China
Abstract: The reproduction of mammal is controlled by a network which composed of neuro-endocrine system. The recent research has demonstrated that Kisspeptins， the protein of KISS-1 gene， and its receptor GPR54 play important roles in this neuro-endocrine network， and have intimate relationship with the onset of puberty， oestrus and ovulation， the switching of oestrus and anestrus of seasonal reproduction animal. Here， the recent research progress of Kisspeptins/GPR54 system in the mammal reproduction regulation is reviewed.
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