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The Pattern of Distribution of Paneth Cells in Intestine of Newborn BALB/c Mice
Wang Zhifeng, Liang Hongde, Kang Jingjing, Zhang Rui, Yang Yurong*
College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China
Abstract: To observe the regularity of distribution of Paneth cells in normal BALB/c mice， 2 d， 4 d， 6 d， 8 d， and 10 d BALB/c mice were selected respectively (n=3 in each group). The distribution and morphology development of Paneth cells in different segments of the small intestines and different time were analyzed by paraffin section， HE staining and Leica microscopic image processing system. Result show that Paneth cells exist only in small intestine of the BALB/c mice， which is less in the duodenum and jejunum， and more in the ileum. The difference among the different segments of the small intestines were statistically significant (P<0.05). 4 days before， the development of small intestine gland is not imperfect， and no Paneth cells were observed in it. After 6 days of birth， Paneth cells were found in small intestine gland. The difference among different ages and were statistically significant (P<0.05).
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