Home > Browse Issues > Vol.33 No.2
Partial Hepatectomy in the Study of Mouse Liver Regeneration
Ming Ma, Zhe-Jin Sheng, Meng-Jie Zhang, Wei-Gang Wang*
School of Life Science and Technology, Tongji University, Shanghai 200092, China
Abstract:
Partial hepatectomy (PH)， a basic protocol， is widely used to study the liver regeneration and tissue regeneration. This article introduced the experimental method of 2/3 PH in detail， used the C57 mice as the subject. In our study， survival rate of the mice after the operation could be to 90%. After PH， the mice liver and body weight ratio gradually increased， and 7~10 days after PH the liver weight can be increased to 90% of the normal liver weight. The hepatocytes stopped dividing after 10 days . The found of 2/3 PH is for us to lay the foundation of the future to study the mechanism of the liver regeneration.
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