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The Applications of Caenorhabditis elegans in Alzheimer Diseases Research
Ping Yang*
School of Life Sciences and Technology, Tongji University, Shanghai 200092, China
Abstract: Caenorhabditis elegans (C. elegans) is an important model organism for biology and medicine research because it is simple， easy to deal with and many human disease related genes could be found in it. The structure of the nervous system in C. elegans is very simple， whereas its neuronal cell types and corresponding neurotransmitters resemble that in mammals. Thus C. elegans is one of the good kinds of models in vivo for the research of neurodegenerative disease including Alzheimer disease. This article reviewed the progress of the applications of C. elegans as a model in Alzheimer diseases research.
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