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The Role of Interleukin-6 in Liver Regeneration
Huan Dou, Jing Gao*
School of Life Sciences, School of Medicine, Nanjing University, Nanjing 210093, China
Abstract: Interleukin-6 (IL-6) is a pleiotropic cytokine exerting multiple biologic activities on different types of target cells. Recently increasing evidence showed that it plays an important role in liver regeneration. IL-6 and its signaling cascade trigger the process of liver regeneration at the priming phase， which is so essential that can not be neglected. In this review， we summarized the IL-6 involved mechanism underlying hepatic proliferation regulation， which will provide some new therapeutic targets for hepatic diseases.
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