Immunoisolation Technology by Cell Microencapsulation in Transplantation Medicine

Abstract: As an effective immunoisolation technology， cell microencapsulation can overcome the dual repelling interactions between the host and donor cells to keep the transplanted cells excreting bioactive substances. Alginate-polylysine-alginate membrane is the most widely used microencapsulation material that can reduce immune repulsion by improving its biological compatibility. Cell microencapsulation， especially with the transgenic cells is playing more and more important role in medical treatments. Cell microencapsulation will have a promising future in various tissue and cell allograft or xenograft despite the needs of technology improvement.

CSTR: 32200.14.cjcb.2004.05.0003