Home > Browse Issues > Vol.26 No.4
Recent Advance in MicroRNA
Chen-Zhuo Feng, Feng Shi*
College of Life Science, Zhejiang University, Hangzhou 310029, China
Abstract: microRNAs (miRNAs) are an abundant class of ~22-nucleotide non-coding RNAs, which are encoded as short inverted repeats in the genomes of diverse organisms. Recent studies showed that miRNAs regulate translation and stability of target mRNAs based on (partial) sequence complementarity during development. The discovery of these novel RNA molecules has generated considerable research interests. miRNA will be a target for the research on the physiology of plant and animal, human pathology and system development. Here, we review the recent studies and progress on the respects of the discovery, functions and mechanisms of the miRNA.