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RNAi and the Stem Cell
Shu-Zhen Zhuang, Wu-Zi Dong, Zhong-Ying Dou*
Shaanxi Province Branch Center of National Stem Cell Engineering & Technology Center, Northwest Sci-tech University of Agriculture and Forestry, Yangling 712100, China
Abstract: RNAi exists in all the cells of organism， whose molecular mechanism has been known theoretically. The technology provides a new method for studying stem cells. The paper reviewed the molecular mechanism， the RNAi phenomena in stem cells， the assay of the effects of RNAi on stem cells and the detection of interference of siRNA with the specific functional genes of stem cells. The review showed that the technological research on RNAi had great prospect in studying the function of genes and the maintenance and specific differentiation regulation of stem cells.
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