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RNA Polymerase Ⅱ Transcription Elongation Factors
LI Fen1, LU Jun*, HUANG Bai Qu
Institute of Genetics and Cytology, Northeast Normal University, Changchun, Jilin 130024, China
Abstract: When RNA polymeraseⅡpasses through the coding region of a gene， it must overcome various kinds of obstacles including the tightly wrapped nucleosomes. Mechanisms to deal with these obstacles clearly exist in cells， because transcription through chromatin is very efficient in vivo. An increasing number of different categories of elongation factors that assist polymeraseⅡin this process have been identified by genetical and biochemical researches. Here we review the advances in studies of elongation factors according to their types and functions.
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