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Transport of Ribosome-inactivating Proteins in the Cell
Feng Wang, Jin-Biao Zhan*
Department of Biochemistry and Molecular Biology, Zhejiang University Medical School, Hangzhou 310031, China
Abstract: Ribosome-inactivating proteins (RIPs) are a group of protein toxins which inhibit protein synthesis in cells. Recently RIPs have been used as molecular probes in cell biology and as anti-cancer and antiviral drugs in clinic. In this review， we focus on the intracellular trafficking and translocation of RIPs based on research recent years.
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