Home > Browse Issues > Vol.27 No.6
Chromosome Condensin
Hui-Zhen Wang, She-Pu Xue, Dai-Shu Han*
Department of Cell Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China
Abstract: Chromosome architecture is an important event in cell cycle. However， the molecular mechanisms in regulating chromosome construction dynamics are unclear. The recent studies on the chromosome condensin have provided new clues to further understand the mechanisms of chromosome architecture. Discovery of the chromosome condensin is believed to be a milestone in cell biology. In the present paper， the discovery history of condensin， its functions in mitosis and meiosis， relations with cohesin and roles in regulating gene expression are reviewed， which should be reference for the investigators in related fields.
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