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Caspase-independent Programmed Cell Death
Zhen-Xia Qin, Feng Gu, Ying-He Hu*
Key Laboratory of Brain Functional Genomics, Ministry of Education & Science and Technology Commission of Shanghai Municipality, East China Normal University, Shanghai 200062, China
Abstract: Programmed cell death (PCD) plays essential role in the development and maintenance of multicellular organisms. It can be defined into various forms (apoptosis， apoptosis-like PCD and necrosis-like PCD). Apoptosis is expounded relatively clearly among them. It is believed that caspases are crucial executors in all programmed cell death. Recently， however， much evidence indicated that some forms of programmed cell death， including apoptosis， can happen without the involvement of caspases. In this review， we summarized caspase-independent programmed cell death.
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