Reform and Practice of Higher-Order Cell Biology ExperimentalTeaching Driven by Research Projectsunder the OBE (Outcome-Based Education) Model
JIANG Shanshan#, ZHAO Qirui#, WANG Yonghua*
To address the fragmented skill training, insufficient student engagement, and disconnectionfrom authentic research contexts in traditional cell biology experimental courses, this study established an advanced, multidisciplinary, comprehensive laboratory course grounded in the OBE (outcome-based education) model, centered on the cutting-edge scientific question: the regulatory role of C9orf72 gene knockout in exosome biogenesis and secretion. A “research project-scaffolding” instructional design was adopted to guide students through acomplete research workflow, including project design, experimental operation, data integration, result interpretation,and report writing, thereby promoting a shift from passive verification to active inquiry. Practical implementationdemonstrates that this model effectively fosters the deep integration of experimental teaching and research innovation, offering a practical reference for the reform of higher-order experimental courses in the life sciences.
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