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The Progress of Microscopic Mechanical Signals and Biotechnology in Tumors


CAO Huimin, LI Xian*

(Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China)
Abstract:

At present, malignant tumors continue to be one of the primary causes of death globally. Modern cancer treatments encompass surgery, chemotherapy, radiotherapy, hormone therapy, immunotherapy, and nutritional supplement therapy. However, owing to the diversity, heterogeneity, and instability of tumors, there is currently no high-precision regulatory approach for tumor diagnosis and treatment. On the microscopic level, biomechanical signals play a role in regulating tumor cell growth behavior and tumor treatment, offering a novel direction for research into the occurrence and development of tumors, as well as precision medicine. Most domestic and foreign studies primarily concentrate on the effects of biochemical factors, neglecting the significant breakthroughs in biomechanics within the realm of biotechnology. This review summarizes the multilevel and multiscale mechanical characteristics of malignant tumors and the advancements in biotechnology-based tumor treatment research.


CSTR: 32200.14.cjcb.2025.05.0021