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Research Progress of Major Immune Cells in Endometriosis


YU Hongbo, LIN Fengqin, WANG Junjie*

(Department of Gynecology, Renhe Hospital Affiliated to China Three Gorges University, Yichang 443001, China)
Abstract:

The pathogenesis of endometriosis has not yet been fully elucidated. Recent studies have indicated that hormones, immune responses, immune cells, and various immune factors are associated with the occurrence and progression of this disease. The pathological growth of ectopic endometrial tissue can lead to functional alterations in certain immune-related cells, contributing to the advancement of endometriotic lesions. Immunological research may pave the way for innovative immunoregulatory therapies for endometriosis. This article reviews the research progress on several major immune cells, including macrophages, dendritic cells, natural killer cells, T cells, and B cells, in endometriosis.



CSTR: 32200.14.cjcb.2025.04.0022