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Research Advances in Polycystic Ovary Syndrome


XIAO Linxi, LIU Yang*, TANG Qiqun*

(Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China)
Abstract:

PCOS (polycystic ovary syndrome) is a common gynecological endocrine disorder that can lead to female infertility. It encompasses diverse clinical symptoms such as irregular or absent menstrual periods, hyperandrogenemia, and PCOM (polycystic ovarian morphology), frequently accompanied by insulin resistance, as well as increased risks of cardiovascular disease and endometrial cancer, which severely affects the quality of life. The etiology of PCOS is complex and remains unclear, involving genetic, endocrine, and metabolic factors. As a result, there is currently no effective cure for the condition, and treatment is mainly tailored to management of specific symptoms. This review summarizes the diagnostic criteria, pathogenesis, and treatment strategies for PCOS, with the aim of gaining a deeper understanding of the disease and providing new insights for clinical diagnosis and management.



CSTR: 32200.14.cjcb.2025.04.0015