The Diagnostic and Therapeutic Values of EBV DNA in Nasopharyngeal Carcinoma
SUN Xuesong, LIU Sailan, MAI Haiqiang*
Nasopharyngeal carcinoma is a malignant tumor with highly uneven geographical distribution, with high incidence areas mainly concentrated in southern China. EBV (Epstein‐Barr virus) infection is closely related to the occurrence and development of NPC. At present, EBV DNA is the most important biomarker for nasopharyngeal carcinoma, and plasma EBV DNA detection has become an important screening tool for early detection of nasopharyngeal carcinoma. For advanced NPC, plasma EBV DNA can also guide the use of PET-CT before treatment. Additionally, EBV DNA is also an important prognostic factor for NPC patients, which can predict the survival and risk of recurrence and metastasis of patients. Based on the level of plasma EBV DNA, NPC patients can be stratified to different risk levels and received personalized treatment plans, further achieving precision medicine for nasopharyngeal carcinoma.
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