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Classification and Functions of ABC Transporters in Yeast
Ji-Hong Wang1#, Xi-Chuan Li2#, Ling-Huo Jiang1,2*
1School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China; 2Tianjin Research Center of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China
Abstract: The classification and characteristics of ATP-binding cassette transporters (ABC transporters) in yeast are introduced， and recent progresses of functional studies on these ABC transporters in pleiotropic drug resistance and lipids trafficking are reviewed. Elucidation of functions of these ABC transporters might help us understand the mechanisms by which drug resistance occurs in pathogenic yeasts including Candida albicans.
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