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Molecular Mechanisms of Nicotine Regulating Apoptosis
Tao Zhang, Han-Hua Cheng*, Rong-Jia Zhou*
Department of Genetics and Center for Developmental Biology, College of Life Sciences, Wuhan University, Wuhan 430072, China
Abstract: Nicotine is a main component in tobacco， which has broad biological significance. Not only does nicotine have effect on the development of nerve， respiratory and cardiovascular systems， but has a complex interaction with carcinogenesis. By regulating apoptosis， nicotine plays an important biological role. This paper mainly reviews the signal pathways and molecular mechanisms of nicotine in apoptotic regulation.
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