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Pathogens and Extranuclear Organelles


YUAN Zhen1, ZHANG Fuhai1, DING Binbin1,2,3*

(1School of Basic Medicine, Huazhong University of Science and Technology, Wuhan 430030, China; 2Guangzhou National Laboratory, Guangzhou 510320, China; 3State Key Laboratory of Respiratory Disease, Guangzhou 510182, China)
Abstract:

Various types of pathogens, such as bacteria, viruses and parasites, have acquired complex strategies in manipulating and modifying various organelles to provide optimal conditions for their survival and reproduction. This review summarizes the virulence mecahnisms and physiological functions of pathogens targeting autophagosomes, lysosome, endoplasmic reticulum, mitochondria, Golgi apparatus, lipid droplets and peroxisome. This review provides the insights for further understanding the pathogenesis and treatment of pathogens.


CSTR: 32200.14.cjcb.2024.01.0015