Research Progress of Mitochondria in the Regulation of Oocyte Developmental Potential
DONG Rui#, GUAN Ruiqi#, GAO Yake#, LANG Qichun, SHEN Junling*, SUN Jianwei*
The quality of oocytes is closely related to female fertility. Mitochondria are the most abundant organelles in oocytes and involved in the development of oocytes and early embryos. The required energy and signal transduction occurring during each critical stage of oocyte maturation largely depend on the function and activity of mitochondria. Mitochondria, due to their crucial role in oocyte and embryonic development, serve as markers for evaluating oocyte viability and quality. Herein, this paper reviews the progress of mitochondrial DNA, mitochondrial dynamics, mitochondrial energy metabolism and mitochondrial quality control that regulate oocyte development, which provides a reference for mitochondrial regulation in reproductive medicine research.
CN
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