Structure and Function of Golgi in Mammalian Cells
XING Yusheng# , JIAN Yannan# , ZHANG Xiaoyan*
In animal cells, the Golgi apparatus is the center of cargo transport in the endomembrane system, responsible for processing, modification and sorting of proteins and lipids. The orderly Golgi structure is the basis for maintaining its precise function. This article summarizes the molecular mechanisms of maintaining the unique stacking and ribbon-like structure of Golgi apparatus in mammalian cells, specifically elaborates on the role of Golgi structure in protein glycosylation modification and sorting, analyzes the correlation between Golgi structure and functional disorders and diseases, and introduces other physiological functions in which the Golgi is involved, based on recent hot research topics. This article provides a reference for a deeper understanding of the structure and function of Golgi apparatus under physiological and pathological conditions.
CN
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