The Advances of Cancer Vaccines
XIE Chunyuan#, YAO Ruhui#, XIA Xiaojun*
As a promising means of antitumor treatment, cancer vaccines elicit effective immune response and the long-term immune memory against tumor, and lead an important research direction in the field of cancer immunotherapy. Cancer vaccines can be categorized into four kinds by different formulations: cell-based vaccines, virus-based vaccines, peptide-based vaccines and nucleic acid-based vaccines. These vaccines can inhibit tumor growth by enhancing the antitumor immune response. This review discusses the mechanism of action and recent advances in basic research and clinical trials of cancer vaccines, aiming to inspire the in-depth understanding of cancer vaccines and promote the development of next-generation cancer vaccines.
CN
EN