Home > Browse Issues > Vol.45 No.10
Advances in the Research of Rac1 in Tumor Drug Resistance
LIU Yuxin, ZHANG Xingli, FANG Dongdong*
(Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China)
Abstract:
Rac1 (Ras-related C3 botulinum toxin substrate 1) is critical for the development and progression of various diseases, including cancer, and it has been shown that Rac1 is associated with drug resistance. This review outlines the role of Rac1 in modulating drug resistance, and the associated mechanisms and available inhibitors, which may provide new options for future therapies targeting cancer drug resistance.
CN
EN