Research on the Mechanism of Exercise Improving Diabetic Kidney Disease
GUO Zongcheng, LAN Tian, MA Luyao, WANG Hao, HE Enpeng*
In the past few decades, more than 50% of patients with DM (diabetes mellitus) developed DKD (diabetic kidney disease), and DKD was also the leading cause of ESKD (end-stage kidney disease). Studies have proved that DKD is a CKD (chronic kidney disease) caused by DM-induced renal metabolic and hemodynamic disorders, and the effect of exercise as a non-drug intervention on DKD has been well studied. Therefore, this article will discuss the impact of exercise on DKD intervention from three aspects, namely, blood glucose homeostasis, oxidative stress and renin-angiotensin-aldosterone system. The aim of this review is to provide clues for future studies.
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