The Role of Toll-Like Receptor Signaling Pathway in Biological Regeneration
KUANG Xiaoxuan, LIANG Yujun*
Regeneration is the process by which an organism regrows or builds back a lost or injured part of the organism. To reveal the regulatory mechanism of regeneration process has become an important topic in the field of biology. TLR (Toll-like receptor) signaling pathway is an important part of the innate immune system, which can recognize pathogen-associated molecular pattern and damage-associated molecular pattern, and has a high degree of homology in different species. In this paper, the molecular mechanism of TLR signaling pathway and its relationship with biological regeneration are reviewed. Current studies on TLR signaling pathway show that it not only plays a role in immune defense, but also participates in the regulation of biological regeneration, and plays a certain function in the regeneration process of various tissues and organs.
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