Research Progress in Non-Coding RNA and ceRNA Regulatory Network in Chronic Obstructive Pulmonary Disease

ZHANG Xinxin¹, PANG Lijian², ZANG Ningzi^1,2, WANG Linlin²*, LÜ Xiaodong¹*

（¹Liaoning University of Traditional Chinese Medicine, Shenyang 110847, China; ²The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China)

Abstract:

The ncRNA (non-coding RNA) and the regulatory networks of ceRNA (competitive endogenous RNA) have been one of the research hotspots in recent years in domestic and international medical industry. Through multi-link, multi-factor and multi-target regulation, they directly or indirectly participate in genomic transcription or post-transcriptional regulation of various diseases. COPD (chronic obstructive pulmonary disease) is a chronic respiratory disease with persistent airflow restriction. This paper summarized the recent research status of ncRNA and ceRNA regulatory network in COPD, and opened up a new research angle and method for the clinical diagnosis and treatment of COPD in the future.

CSTR: 32200.14.cjcb.2023.09.0016