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The Structure of Kininogen-1 and Its Research Progress in Diseases
CUI Jiabo, YOU Chongge*
(Laboratory Medicine Center, Lanzhou University Second Hospital, Lanzhou 730030, China)
Abstract:
KNG1 (kininogen-1) protein, also known as high molecular HK (weight kininogen) (P01042), is encoded by the KNG1 gene. While participating in the coagulation process, it also plays an important role in cardiovascular, respiratory, digestive, and other systemic diseases. Therefore, this paper provides a review of the structure of KNG1 and its mechanism of action in diseases, aiming to provide a more comprehensive knowledge of KNG1 and to realize the possibilities of KNG1 in clinical diagnosis and treatment.
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