Research Progress on Nucleolin in Cardiovascular Disease
TU Junchu#, WANG Yanli#, LU Lin, WU Chengjie, ZHANG Yu, LI Yangxin*
The cardiovascular diseases are the leading cause of death worldwide. Although traditional treatment can prolong the life of patients, it is associated with many risks. Therefore, new treatments targeting a universal target are needed to achieve a better effect. Nucleolin is a widely expressed and highly conserved protein, which is abnormally expressed in the pathological process of various cardiovascular diseases. Its abnormal expression directly affects the function of the cells, suggesting that nucleolin is a potential therapeutic target for cardiovascular diseases. This paper reviews the role of nucleolin in the occurrence and development of cardiovascular diseases.
CN
EN