Cultures and Applications of Lung Organoids
WANG Xianglong, TIAN Yushan, CHEN Huan, HOU Hongwei, HU Qingyuan*
Lung organoids are mainly formed by stem cells or specific progenitor cells through 3D culture, which can simulate the structure and functions of lung in vitro, and have high tissue origin with human lung tissue. With the development of lung organoids, there are many culture methods, but there is no unified standard. However, studies on lung organoids have been carried out in many fields such as disease research, drug screening and toxicological evaluation. This paper mainly reviews the cultures and applications of lung organoids, in order to provide a certain reference for the development of lung organoids.