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The NF-κB Signal Pathway of Insects
Xin-Min Lu, Gong-Yin Ye*
Institute of Applied Entomology, Zhejiang University, Hangzhou 310029, China
Abstract: In insects， the NF-κB signal pathway， being composed of toll path and imd path， regulates the expression of antimicrobial genes as NF-κB factors binding kB sequence of targeted genes. Evidences have proved that this pathway plays a vital role in insect innate immunity， and can be triggered by proinflammatory microbes and viruses. In this article， the signal elements of this signal pathway in insects are reviewed mainly.
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