Home > Browse Issues > Vol.28 No.4
Molecular Mechanism of Helicobacter pylori Infection
Qing Gu1, 2*, Mu-Yuan Zhu2
1Department of Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, China;2College of Life Sciences, Zhejiang University, Hangzhou 310012, China
Abstract: Helicobacter pylori colonizes the human gastric epithelium and is responsible for gastritis， peptic ulcer， and gastric cancer. In recent years， with publish of the complete genome sequence of H. pylori and deep research of functional genes of this organism， the molecular mechanism of H. pylori infection and the immune response are more in depth understanding. In the paper， We summarize the characteristic of H. pylori genome and molecular mechanism which H. pylori infect human by adhere to the gastric cells and a unique set of virulence factors.
CN
EN