Research Progress on Genome Sequencing and Biosynthesis Pathway of Bioactive Substances in Medicinal Plants

QI Zengxing^1,2,3, LI Junling^1,2,3, HE Qizouhong^1,2,3, LU Liang^1,2,3, LI Ruili^1,2,3*

( ¹National Engineering Laboratory for Tree Breeding, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China; ²Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China; ³The Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China)

Abstract:

Medicinal plants have a wide range of medicinal values due to various types of bioactive substances. The protection and development of their resources have been paid more and more attention. With the completion of genome sequencing of many medicinal plants, it is possible to further study the biosynthesis pathway of medicinal active substances and the key enzyme genes at the molecular level. This review mainly introduced the development history of genome sequencing technologies and its research status in medicinal plants, with special emphasis on the important bioactive substances of medicinal plants and their key enzyme genes in synthesis pathway. This will provide valuable information for further clarifying the molecular mechanism of bioactive substances synthesis and regulation in the future, and lay a perfect foundation for fully exploiting and utilizing the medicinal functions of medicinal plants.

CSTR: 32200.14.cjcb.2022.02.0020