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The Reciprocal Interactions between Natural Killer Cells and Dendritic Cells
De-Kuang Zhao1, Qing-Qing Wang1, Xue-Tao Cao1,2*
1Institute of Immunology, Zhejiang University, Hangzhou 310031, China; 2Institute of Immunology,Second Military Medical University, Shanghai 200433, China
Abstract: The functional links between natural killer (NK) cells and dendritic cells (DCs) have been extensively investigated in recent years. By secreting cytokines and through cell-to-cell contact manner， NK cells and DCs can interact with each other in inflamed tissues and second lymphoid organs， which process is involved in anti-tumor， anti-viral effects and transplantation rejection. Here we reviewed the process they interact and the biological functions they exhibit in innate and adaptive immune responses.
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