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The Relationship between mRNA Structure and Its Stability
Gao-Fei Xiong1.2, Xiang-Yang Xiong2, Ji-Xiang Zhang1*
1Department of Digestion, the Key Laboratory of Molecular Medicine, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, China; 2Department of Physiology, Department of Biochemistry, Basical Medical College,Nanchan
Abstract: mRNA structure is closely correlated with mRNA stability which is involved in the regulation of gene expression. To better understand the molecular mechanisms of gene expression， the relationship between mRNA structure， including 5'' cap structure， 3'' poly(A) tail， 5'' untranslated region et al.， and mRNA stability was reviewed in this work.
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