Cell Competition and Tumour
YUAN Jiawei, LI Yuchen, TANG Kaijie, HOU Ni*
“Cell competition” is a series of cell interactions that make cells compete for survival and space in tissues, leading to “winner cells replacing loser cells”. Some promote tumour development, while others inhibit carcinogenesis and cancer progression, such as EDAC (epithelial defense against cancer). Through researches of cell competition and its regulatory mechanism in specific tumour, new strategies for cancer prevention and treatment would be provided. This paper reviews the current research status of the effects and influencing factors of cell competition on carcinogenesis and cancer progression, and puts forward new prospects for tumour prevention and treatment, to provide support for tumour prevention and treatment.
CN
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