Application of Natural Products and Nutritional Supplements in Diabetic Muscular Atrophy

HUANG Jielun¹, LIANG Jiling¹, ZHANG Hu¹, LÜ Jun¹, ZHOU Jingtao², CHEN Ning³*

（¹Graduate School, Wuhan Sports University, Wuhan 430079, China; ²School of Physical Education, Hunan University of Science and Technology, Xiangtan 411201, China; ³Tianjiu Research and Development Center for Exercise Nutrition and Foods,

Abstract:

Skeletal muscle as an important part of the body, most of the glucose metabolism in carbohydrate metabolism are induced by insulin through skeletal muscle. Skeletal muscle metabolic disorders affect the glucose metabolic homeostasis of the body and the sensitivity of insulin, while diabetic muscular atrophy is a secondary disorder of muscle tissue caused by diabetes. At present, besides routine treatments of diabetic muscular atrophy with the combination of Western medicine and traditional Chinese medicine, some non-drug (such as natural products) and nutritional supplements also play an important role in the prevention and treatment of diabetic muscular dystrophy. This article will discuss the definition, pathogenesis and signaling pathway of diabetic muscular atrophy, as well as some natural products and nutritional supplements for the prevention and treatment of it. This article is expected to provide more theoretical references for the non-drug targeted therapy of diabetic muscular atrophy.

CSTR: 32200.14.cjcb.2021.09.0024