The Process and Application of Nucleocytoplasmic Transport of Proteins
DAN Demiao, GUO Zhongjian*
One of the characteristics that distinguish eukaryotes from prokaryotes is the presence of the nuclei. The NE (nuclear envelope) is a phospholipid bimolecular membrane, including inner membrane and outer membrane. The NPC (nuclear pore complex) embedded in the NE is necessary for the process of transportation of some proteins through the NE. In addition, the process also requires the coordination of the transport receptor protein, the Ran system, and the structure of cargo protein. This article focuses on the process and mechanism of eukaryotic nucleocytoplasmic transport and the clinical application of transport receptor proteins in tumor therapy in recent years.
CN
EN