Research Progress of Neurotoxicity Induced by Silver Nanoparticles
LI Yutong, XUE Yuying*
AgNPs (silver nanoparticles) are widely used in the early diagnosis of tumors and the diagnosis and treatment of nervous system diseases. However, nanoparticles can be transported into the central nervous system through a variety of ways, and may be accumulated in nerve tissue, leading to nerve cell dysfunction and neurodegenerative diseases. This review describes the brain cumulative effect of AgNPs and the pathway of AgNPs entering the central nervous system, mainly including the olfactory nerve and blood-brain barrier pathway; expounds the influence of AgNPs on the central nervous system and the mechanism of neurotoxicity, so as to provide basis and reference for further study on the neurotoxic mechanism of AgNPs and safety evaluation.
CN
EN