The Application of Single Cell Technology and Stem Cell-Based Therapy in Cardiac Disease
FENG Qi1,2, WANG Li1,2*
Cells are the basic unit of life, and heterogeneity is one of the inherent properties of cells. The emergence of single-cell RNA sequencing technology facilitates the study of intercellular heterogeneity, the discovery of new cell populations, and the reconstruction of developmental trajectories. Currently, driven by single-cell RNA sequencing technology, there have been many new advances in the field of myocardial infarction, hypertrophy, and heart failure. This review summarizes the process of single-cell RNA sequencing, including sample preparation, library construction and sequencing analysis, reviews its application in heart diseases, and discusses the clinical prospect of stem cell-based therapies.
CN
EN