Home > Browse Issues > Vol.43 No.5
The Regulating Role of ROS in Tumorigenesis and Anti-Tumor Drugs
YANG Daning, LIU Jinjuan*
(Key Lab of Biotechnology for Medicinal Plants of Jiangsu Province, School of Life Science, Jiangsu Normal University, Xuzhou 221116, China)
Abstract:
ROS (reactive oxygen species) are small reactive oxygen-derived molecules. The increase in ROS concentration can damage cells and cause many diseases including tumor. The high level of ROS in tumor cells has become a potential target for the treatment of tumors. Small molecules that can regulate the level of ROS in cells can be screened for the development of anti-tumor drugs. This article mainly reviews the role of ROS in the process of tumor cell proliferation, apoptosis, metastasis and invasion, and its role in the development of anti-tumor drugs, so as to provide ideas for tumor prevention and the development of anti-tumor drugs.
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