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Research Progress of Pheophorbide a-Photodynamic Therapy Against Prostate Cancer
XIE Liguo, TAN Wenli, ZHU Guodong, WEI Yunlin*
(Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China)
Abstract:
Pheophorbide a is the compound extracted from higher plant and marine algae. It shows antibacterial, anti-inflammatory, antiviral, antioxidant and anti-tumor effects. As a natural photosensitizer, pheophorbide a exhibits good inhibitory effect on a variety of tumors in combination with photodynamic therapy. In recent years, some great progresses have been made in cancer treatment, especially showing great potential in anti-prostate cancer. The structural characteristics, applications, and the mechanism of pheophorbide a-photodynamic therapy against prostate cancer are briefly reviewed in this paper.
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