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Structure and Biology Function of T-STAR
Bing Chen*, Lian Guo, Ling Zhang, Feng-Tian He1
Endocrinology Department of Southwest Hospital, 1 Biochemistry Institute,Third Military Medical University, Chongqing 400038, China
Abstract:
The gene of T-STAR is located in chromosome 8q24.2. Its expression product is about 55 kDa Sam68 analog—a new member of STAR family. T-STAR is an RNA-binding protein that has an RNA-binding domains and function region of tyrosine phosphorylation. T-STAR has been shown to be involved in spermatogenesis， regulation of cell proliferation or immortalization of transform cell by the pathways including tyrosine kinase signal transduction and pre-mRNA alternative splicing or activation of RNA. It is also thought to be related with some diseases.
The gene of T-STAR is located in chromosome 8q24.2. Its expression product is about 55 kDa Sam68 analog—a new member of STAR family. T-STAR is an RNA-binding protein that has an RNA-binding domains and function region of tyrosine phosphorylation. T-STAR has been shown to be involved in spermatogenesis， regulation of cell proliferation or immortalization of transform cell by the pathways including tyrosine kinase signal transduction and pre-mRNA alternative splicing or activation of RNA. It is also thought to be related with some diseases.
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