The Research of Clinical Separation of SVF (Stromal Vascular Fraction)
LI Zhiguo, ZHANG Fangfang, LIU Yue, LIU Jianxing, JIN Liang*
Adipose tissue is an important source of stem cells because it is easy to access and has a good histocompatibility and little influence on donors. SVF (stromal vascular fraction) is a heterogeneous group of cells isolated from adipose tissue, including ADSC (adipose derived stem cell) and stromal cells. According to a large number of clinical trials, SVF has been proved that it can promote tissue to repair and regenerate, especially in cosmetic surgery and tissue repair. In the early stage, SVF was obtained by enzyme digestion. With the extensive application of SVF in clinical practice during recent years, in order to ensure patient safety and quality control, some new automatic separation equipment was developed. Meanwhile, in order to meet the regulatory requirements of some countries and avoid the use of enzyme, non-enzymatic digestion method becomes a way of obtaining SVF. Therefore, current essay is primary to make a detailed discuss about reported clinical separation ways and related equipments based on the enzyme digestion and non-enzyme digestion.
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