Research Progress of REG Protein in Pancreatic Cancer
NIE Yuanhua, CHEN Minxue, ZHAO Zhiqiang, MA Fulin, ZHU Zhandi, LI Xiaojun, FAN Yong, KANG Boxiong, KANG Yingxin, WANG Chen*
PC (pancreatic cancer) is an common digestive cancer. When diagnosed, the stage of PC is late due to little specific symptom. Meanwhile, surgery can hardly be performed on late-stage PC patients and the efficacy of chemotherapy barely meets the satisfaction. The mortality of PC is high. REG protein coded by REG gene belongs to small secretory protein family. The level of REG protein will increase, when body has inflammation. REG protein can also alter the tumor cell proliferation and anti-apoptosis. The relation between REG protein and PC is close. Understanding the association between REG protein and PC will have a crucial meaning to oncogenesis, diagnosis, treatment and prognosis of PC.
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