Correlation Analysis of IL-6 and CRP Combined with PCT of Serum with the Severity and Prognosis of Sepsis Patients
CHEN Xide*, LIN Zhihong, HUANG Yanjing
This study aimed to study the value of serum levels of IL-6 and CRP combined with procalcitonin in evaluating the severity and prognosis of sepsis patients. A total of 106 patients with sepsis admitted to our hospital from December 1, 2016 to December 1, 2019 were selected. Serum levels of IL-6, CRP and PCT were detected within 24 h upon admission, and SOFA score was also performed. Within 28 days after admission, the patients were divided into the survival group and the death group according to the survival outcome, and the patients were judged whether they had MODS (multiple organ dysfunction syndrome). The correlation between serum levels of IL-6, CRP and PCT and severity and prognosis was detected. Compared with the survival group, the serum levels of IL-6, CRP and PCT in the death group were higher on average, with statistically significant differences (P<0.05). The proportion of patients with MODS in the death group was higher than that in the survival group, and the difference was statistically significant (P<0.05).The results of the combined detection of IL-6, CRP and PCT were better than those of any single indicator. Serum levels of IL-6, CRP and PCT were positively correlated with SOFA score and the rate of poor prognosis. Serum IL-6, CRP combined with PCT level has clinical value in predicting the severity and prognosis of sepsis patients.
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