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Drosophila Germline Stem Cells and Their Microenvironment
Zhen-Yue Feng, Min-Hui Pan*, Cheng Lu
Key Sericultural Laboratory of Agriculture Ministry, College of Sericulture and Biotechnology, Southwest University, Chongqing 400716, China
Abstract: Stem cells microenvironment is considered to be composed of tissue cells and extracellular substrates that can indefinitely house one or more stem cells and control their self-renewal and prevents their differentiation . Stem cells can only multiply and maintain self-renewal in a specific niche. Studies using the model biology Drosophila germline stem cells niche system have revealed that support cells and their signaling pathways in the microenvironment play a vital role in controlling the fate of the stem cells.
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